AI systems are evolving from copilots to autonomous, multi-agent architectures, expanding the attack surface across tool execution, persistent memory, and inter-agent communication. This hands-on session extends copilot security methods to agentic ecosystems, covering threat modeling for multi-agent pipelines, supply-chain defenses, safeguarding sensitive workflows, and prompt injection at scale. Through real-world case studies—independent and integrated assistant deployments—you’ll learn to implement policy-as-code guardrails, fine-grained access controls, and red-team strategies for agent behavior. Whether you’re securing or penetrating AI workflows, you’ll leave equipped with actionable patterns to defend and harden end-to-end autonomous systems without stifling innovation.